Tóm tắt

Bacground: The relationship between serum anti-cardiolipin (aCL) antibody correlates with some risk factors and severity level in patients with cerebral infarction. Subjects and Methods: cross-sectional descriptive study, 68 patients with acute cerebral infarction at Hue University Hospital. Data processing method according to usual medical statistics and SPSS 16.0. Results: (1) The proportion of positive and serum antibody levels in patients with acute cerebral infarction: (i) aCL-IgG antibody (+) accounted for 20.6%; aCL-IgM (+) accounted for 7.4% ; (ii) The average concentration of the aCL-IgG (+) was 33.98 ± 29.42 GPL/mL and aCL-IgM (+) was 26.58 ± 10.30 MPL/mL. (2) The relationship between the aCL antibody concentration with some associated risk factors and the severity of acute cerebral infarction: (i) There was a close correlation between aCL-IgG levels (r = 0.709; p < 0.01); inverse correlation with Glasgow Coma Scale (r = -0.643; p < 0.01); (ii) There was an average inverse correlation between the concentration of aCL-IgM with size of injury (r = 0.407; p < 0.01); and average inverse correlation with Glasgow Coma Scale (r = -0.393; p <0.01); (iii) There was an average inverse correlation between the concentration of IgM aCL-with cholesterol levels (r = -0.31 and p <0.05) and LDL-C levels (r = 0.25 and p <0.05); (iv) There was no correlation between the aCL-IgG concentrations with level of lipid profiles; (v) There was no correlation between aCL IgG/IgM concentrations with level of other indicators: glucose, hs-CRP, fibrinogen, urea, creatinine, platelet count, blood pressure of acute cerebral infarction patients. Conclusion: aCL antibody of serum was high and correlated with severity of acute cerebral infarction.

Từ khoá

Toàn văn

PDF

Trong số này