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Background: Serum High sensitivity C-reactive protein (Hs-CRP) is an important inflammatory marker in patients with chronic renal failure. The increase in Hs-CRP levels in patients with chronic renal failure increases the speed of progression to end-stage renal failure in patients with chronic renal failure and increased cardiovascular risk in patients with chronic renal failure. Objectives: 1) To survey the concentration of serum Hs-CRP in patients with chronic renal failure who were treated by conservative therapy; 2) To survey the correlation of concentration of serum Hs-CRP with concentration of serum creatinine and albumin in patients with chronic renal failure who were treated by conservative therapy. Methodology: A cross-sectional study. Results: 1) The concentration of serum Hs-CRP in patients with chronic renal failure who were treated by conservative therapy was 45.61 ± 19.48 mg/L and the concentration of serum Hs-CRP of the control group was 1.56 ± 0.77 mg/L. The diffrence has statistical significance (p <0.001); 2) The concentrations of serum Hs-CRP in patients with chronic renal failure who were treated by conservative therapy positively correlated with serum creatinine concentrations and inversely correlated with serum albumin level. Key words: Hs-CRP, chronic renal failure, conservative therapy

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