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Objectives: To identify factors contribute to help seeking behavior of and understand the perception and attitude of patients with depression, and their service utilisation of people with depression in mental health service. Methodology: Both qualitative and quantitative methods were used in the study. 50 clients who were diagnosed with depression by (ICD-10) and recruited by convenient sampling method. Questionnaires were built in addition to references of similar previous research. Descriptive statistic method were used for data analysis in quantitative research. Thematic analysis of the data in qualitative research was conducted using a framework analysis method. Results: Quantitative research shows that first help-seeking behavior at specialized health service were only 28%, meanwhile 24% pursuits general local health service. The role of religious source of help (traditional healers, fortune-tellers) as first help-seeking behavior was significant at 26%, its ranked as the second choice for clients when first symptoms occur. Most patients with depression have appropriate attitude towards their illness, in particular, not being stigmatized and not isolated from others, the need of long-treatment and the avoidant of stressful responsibility and career. Qualitative research displays common patterns from themes emerged from the analysis: (1) First symptoms of depression, first contact to source of help; (2) Major obstacles accessing to professional mental health care; (3) Perception on the cause of depression; and (4) Change of attitude and practice of help-seeking behavior after being diagnosed as depression. Conclusions: People with depression in Thua Thien Hue province are less likely to access professional care as source of help for their first episode. Factors found to contribute to help seeking behavior include knowledge of health service and mental health problems, social-economic status, and service availability.

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