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Genital tract infection is the most common cause that makes women see the gynecologists and this is also one of the important reasons leading to infertility. Early diagnosis and prompt treatment of genital infection is one of the effective managements to prevent infertility later on. Objective: This study aims to identify the lower genital tract infection in cases of infertility, and understand the involved factors. Subjects and Methods: descriptive cross – sectional study on 92 cases of infertility visited the Hue University Hospital through clinical examination, wet-mount and gram staining, as well as microbiological culture from vaginal discharge, Chlamydia testing with samples from the cervix, serological tests for syphilis also were done. Results: Prevalence of lower genital tract infection is 42.4%. The mean age of subjects is 29.29 ± 5.97, the average time of infertility is 2.83 ± 2.47.The most common disorder is vulvo-vaginal infection; the popular pathogens are bacterial vaginosis, Candida and Chlamydia. Factors associated with lower genital tract infection such as age, occupation, education, geography, classification of infertility, routine vaginal douching, water source for hygiene, history of lower genital tract infections. Conclusions: the lower genital tract infections account for a significant proportion in the case of infertility. The diagnosis and treatment of these disorders is necessary to get pregnancy easier as well as to prevent the fetus from infection.

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