Tạp chí Y Dược học - Tập 11 (07) năm 2021
Le Thi Kieu Loan, Nguyen Van Dung, Ngo Thi Kim Cuc
2021 - Tập 11 (07), trang 33
Background: In Vietnam, a number of recent epidemiological studies demonstrated that the prevalence of antibiotic-resistant bacteria has been rapidly increasing, especially in intensive care units (ICUs). The implementation of comprehensive and long-term measures through antibiotic stewardship programs (AMS) is necessary.
Objectives: For patients in the ICU of Hue University of Medicine and Pharmacy Hospital: (1) To survey of usage of antibiotics, and (2) to find out patient-related factors for antibiotic use.
Materials and methods: A cross-sectional study was carried out on 102 medical records of patients who were treated in the ICU from 01/2019 to 10/2020, at Hue University of Medicine and Pharmacy Hospital.
Results: The average age of patients was quite high at 70.71±19.70 years. Initial antibiotic with monotherapy accounted for 41.2%, mainly was ceftriaxone (28 prescribed), combined two antibiotics accounted for 49.0%, the most popular was the combination of third generation cephalosprins with fluoroquinolones. Most of participants prescribed a total of two or three types of antibiotics in their medical records (accounted for 68.6%). Patient-related factors associated with antibiotics usage included: antibiogram results (OR=4.7, p=0.039), sepsis diagnosis (OR=12.0, p=0.04), and initial therapeutic change (OR=14.5, p=0.002).
Conclusion: The majority of initial antibiotic therapies are monotherapy and a combination of two antibiotics in accordance with the recommendation. The number of used antibiotics were associated with the sepsis diagnosis, antibiogram results, and changing antibiotic therapy
Le Thi Kieu Loan, Nguyen Van Dung, Ngo Thi Kim Cuc. (2021). Usage of antibiotics in the Intensive Care Unit at Hue University of Medicine and Pharmacy Hospital. Tạp chí Y Dược học, , 33. DOI: 10.34071/jmp.2021.7.5
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